Article
Measles virus genetic evolution throughout an imported epidemic outbreak in a highly vaccinated population.
Virus research - 22 Jan 2015
Muñoz-Alía Miguel Ángel, Fernández-Muñoz Rafael, Casasnovas José María, Porras-Mansilla Rebeca, Serrano-Pardo Ángela, Pagán Israel, Ordobás María, Ramírez Rosa, Celma María Luisa
Abstract excerpt
Measles virus circulates endemically in African and Asian large urban populations, causing outbreaks worldwide in populations with up-to-95% immune protection. We studied the natural genetic variability of genotype B3.1 in a population with 95% vaccine coverage throughout an imported six month measles outbreak. From first pass viral isolates of 47 patients we performed direct sequencing of genomic cDNA. Whilst no...
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