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Article

Antigenic Drift Defines a New D4 Subgenotype of Measles Virus.

Journal of virology - 1 Jun 2017

Muñoz-Alía Miguel Ángel, Muller Claude P, Russell Stephen J

Abstract excerpt

The measles virus hemagglutinin (MeV-H) protein is the main target of protective neutralizing antibodies. Using a panel of monoclonal antibodies (MAbs) that recognize known major antigenic sites in MeV-H, we identified a D4 genotype variant that escapes neutralization by MAbs targeting the neutralizing epitope (NE) antigenic site. By site-directed mutagenesis, L249P was identified as the critical mutation...

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Identifiers

PMID: 28356529
DOI: 10.1128/JVI.00209-17
PMCID: PMC5432853

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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