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Impact of genotypic variability of measles virus T-cell epitopes on vaccine-induced T-cell immunity

20 Feb 2025

Abstract excerpt

After the COVID-19 pandemic, significant increases in measles cases were observed globally. Community-wide vaccination remains the most effective strategy for preventing measles. However, it is crucial to understand whether prevalent genotypes, when circulating in populations with suboptimal vaccination coverage, may undergo adaptive mutations that allow them to escape vaccine-induced immunity. In this study, a...

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PMID: 39979288
DOI: 10.1038/s41541-025-01088-y

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