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Article

Multiplex SNaPshot-a new simple and efficient CYP2D6 and ADRB1 genotyping method.

Human genomics - 23 Apr 2016

Ben Songtao, Cooper-DeHoff Rhonda M, Flaten Hanna K, Evero Oghenero, Ferrara Tracey M, Spritz Richard A, Monte Andrew A

Abstract excerpt

BACKGROUND: Reliable, inexpensive, high-throughput genotyping methods are required for clinical trials. Traditional assays require numerous enzyme digestions or are too expensive for large sample volumes. Our objective was to develop an inexpensive, efficient, and reliable assay for CYP2D6 and ADRB1 accounting for numerous polymorphisms including gene duplications. MATERIALS AND METHODS: We utilized the multiplex...

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Share to Aged, 80 and over
Share to Cytochrome P-450 CYP2D6

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Copy Number Variations

Share to Gene Duplication

Share to Genotyping Techniques

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Share to Polymorphism, Genetic

Share to Receptors, Adrenergic, beta-1

Source

Open in PubMed Open full text

Identifiers

PMID: 27108086
DOI: 10.1186/s40246-016-0073-3
PMCID: PMC4842286

Genes

ADRB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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