Article
SNaPshot for pharmacogenetics by minisequencing.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2005
Bender Klaus
Abstract excerpt
Genetic polymorphisms of genes coding for metabolic enzymes are helpful to predict how an individual may respond to medication or drugs. The described approach for the identification of genetic variations for the cytochrome P450 enzymes CYP2D6 and CYP2C19 has been designed for the rapid genotyping of relevant alleles (CYP2D6*1, -*3, -*4, -*6, -*7, and -*8 and CYP2C19*1, -*2, -*3, -*4, and -*5) by performing...
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