Article
Association between the IFNA1 (-2Cx2192;T) Polymorphism and Increased IFNAR1 Gene Expression Levels in Chronic Hepatitis B Infection.
Intervirology - 1 Jan 2015
Santos Joelma Carvalho, de Deus Dayse Maria Vasconcelos, de Moura Izolda Maria Fernandes, Lopes Edmundo Pessoa, Alves Maria Rosileide Bezerra, Coêlho Maria Rosângela Cunha Duarte
Abstract excerpt
BACKGROUND: Single nucleotide polymorphisms and variant expression of some interferon (IFN) genes in individuals with chronic hepatitis B virus (HBV) infection might be related to higher viral load and disease complications. Thereby, whole blood samples of 208 patients (94 chronic HBV-infected patients and 114 HBV immune subjects) were analyzed to investigate the association between IFNG (-5Ax2192;G), IFNA1...
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