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Article

Association of an IFN-γ variant with susceptibility to chronic hepatitis B by the enhancement of HBV DNA replication.

Cytokine - 1 Jul 2021

Ben Selma Walid, Laribi Ahmed Baligh, Alibi Sana, Boukadida Jalel

Abstract excerpt

Interferon gamma (IFN-γ) is a crucial cytokine in host immune response to hepatitis B virus (HBV) infection. This study aimed to determine whether a functional polymorphism +874T/A in IFN-γ gene linked to high and low producer phenotypes [IFN-γ (+874Thigh → Alow)] may alter the outcomes of chronic HBV infection in Tunisian population. The +874T/A was analysed by ARMS-PCR method in the group of 200 patients...

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Share to DNA Replication
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 33896709
DOI: 10.1016/j.cyto.2021.155525

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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