Article
Interferon gamma gene polymorphisms and chronic hepatitis B infections in an Iranian population.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology - 1 Jul 2020
Heidari Zahra, Moudi Bita, Mahmoudzadeh-Sagheb Hamidreza
Abstract excerpt
BACKGROUND AND AIMS: Chronic hepatitis B is an important health problem in all countries. I Interferon gamma is a pro-inflammatory Th1 cytokines, which can exert antiproliferative and antitumor activity. Some SNPs in IFN-γ and IFN-γR1 genes may influence the susceptibility to HBV. Here, we evaluated the impact of interferon gamma (+874 T/A) and its receptor (-611A/G, +189G/C and +95C/T) polymorphisms and the risk...
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