Article
Association of interferon-alpha gene polymorphisms with chronic hepatitis B virus infection.
International journal of immunogenetics - 1 Dec 2013
Kimkong I, Tangkijvanich P, Hirankarn N
Abstract excerpt
In this study, the association between the risk of chronic hepatitis B virus infection and the polymorphisms within promoter regions of IFN-α1 and five genes was explored. This association study was performed on 180 Thai patients with chronic HBV infection [hepatocellular carcinoma (HCC) = 65 and non-HCC = 115], 173 individuals with self-limited HBV infection and 140 healthy controls. Our results showed that the...
Topics
- Adult
- Aged
- Alleles
- Asian People
- Carcinoma, Hepatocellular
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Hepatitis B virus
- Hepatitis B, Chronic
