Article
Polymorphisms of type I interferon receptor 1 promoter and their effects on chronic hepatitis B virus infection.
Journal of hepatology - 1 Feb 2007
Zhou Jie, Lu Liwei, Yuen Man-Fung, Lam Ting-Wa, Chung Chi-Ping, Lam Chun-Lit, Zhang Bin, Wang Song, Chen Yu, Wu Sharon H W, Poon Vincent K M, Ng Fai, Chan Chris C S, Jiang Shibo, Yuen Kwok-Yung, Zheng Bo-Jian
Abstract excerpt
BACKGROUND/AIMS: Exposure to HBV leads to a distinct clinical course which is partially pertained to host genetic variability. We aimed to study polymorphisms of type I interferon receptor 1 (IFNAR1) promoter and their potential effects on chronic HBV infection. METHODS: Polymorphisms of IFNAR1 promoter were identified in 320 chronic hepatitis B patients, 148 spontaneously recovered individuals, 148 healthy...
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