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Article

COMT, BDNF, and DTNBP1 polymorphisms and cognitive functions in patients with brain tumors.

Neuro-oncology - 1 Oct 2016

Correa Denise D, Satagopan Jaya, Cheung Kenneth, Arora Arshi K, Kryza-Lacombe Maria, Xu Youming, Karimi Sasan, Lyo John, DeAngelis Lisa M, Orlow Irene

Abstract excerpt

BACKGROUND: Cognitive dysfunction is common among patients with brain tumors and can be associated with the disease and treatment with radiotherapy and chemotherapy. However, little is known about genetic risk factors that may moderate the vulnerability for developing cognitive dysfunction. In this study, we examined the association of single nucleotide polymorphisms (SNPs) in the catechol-O-methyl transferase...

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Source

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Identifiers

PMID: 27091610
DOI: 10.1093/neuonc/now057
PMCID: PMC5035520

Genes

COMT
BDNF
DTNBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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