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Article

Catechol-O-methyltransferase genotype modulates cancer treatment-related cognitive deficits in breast cancer survivors.

Cancer - 1 Apr 2011

Small Brent J, Rawson Kerri Sharp, Walsh Erin, Jim Heather S L, Hughes Tiffany F, Iser Lindsay, Andrykowski Michael A, Jacobsen Paul B

Abstract excerpt

BACKGROUND: Recent attention has focused on the negative effects of chemotherapy on the cognitive performance of cancer survivors. The current study examined modification of this risk by catechol-O-methyltransferase (COMT) genotype based on evidence in adult populations that the presence of a Val allele is associated with poorer cognitive performance. METHODS: Breast cancer survivors treated with radiotherapy (n...

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Identifiers

PMID: 21425136
DOI: 10.1002/cncr.25685

Genes

COMT

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Catechol-O-methyltransferase genotype modulates cancer treatment-related cognitive deficits in breast cancer survivors.PMID 21425136Read ↗

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An association between the allele coding for a low activity variant of catechol-O-methyltransferase and the risk for breast cancer.Semantic proximity Read ↗

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