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Genetic variants and cognitive functions in patients with brain tumors

22 May 2019

Abstract excerpt

BACKGROUND: Patients with brain tumors treated with radiotherapy (RT) and chemotherapy (CT) often experience cognitive dysfunction. We reported that single nucleotide polymorphisms (SNPs) in the APOE, COMT, and BDNF genes may influence cognition in brain tumor patients. In this study, we assessed whether genes associated with late-onset Alzheimer's disease (LOAD), inflammation, cholesterol transport, dopamine and...

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PMID: 31123752
DOI: 10.1093/neuonc/noz094

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