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Article

Characterisation of the Phosphatidylinositol 3-Kinase Pathway in Non-Small Cell Lung Cancer Cells Isolated from Pleural Effusions.

Oncology - 1 Jan 2016

Puglisi Martina, Stewart Adam, Thavasu Parames, Frow Michael, Carreira Suzanne, Minchom Anna, Punwani Ravi, Bhosle Jaishree, Popat Sanjay, Ratoff Jonathan, de Bono Johann, Yap Timothy Anthony, O''Brien Mary, Banerji Udai

Abstract excerpt

OBJECTIVES: We hypothesised that it was possible to quantify phosphorylation of important nodes in the phosphatidylinositol 3-kinase (PI3K) pathway in cancer cells isolated from pleural effusions of patients with non-small cell lung cancer (NSCLC) and study their correlation to somatic mutations and clinical outcomes. MATERIALS AND METHODS: Cells were immunomagnetically separated from samples of pleural effusion...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glycogen Synthase Kinase 3 beta

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Share to Neoplastic Cells, Circulating

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Share to Pleural Effusion, Malignant

Share to Ribosomal Protein S6 Kinases, 70-kDa

Source

Identifiers

PMID: 27082424
DOI: 10.1159/000444928

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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