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Article

PAK1 as a Potential Therapeutic Target in Male Smokers with EGFR-Mutant Non-Small Cell Lung Cancer.

Molecules (Basel, Switzerland) - 27 Nov 2020

Chung Jae Heun, Kim Taehwa, Kang Yong Jung, Yoon Seong Hoon, Kim Yun Seong, Lee Sung Kwang, Son Joo Hyung, Son Bongsoo, Kim Do Hyung

Abstract excerpt

P21-activated kinases (PAKs) are serine/threonine protein kinases that contribute to several cellular processes. Here, we aimed to determine the prognostic value of PAK1 and its correlation with the clinicopathological characteristics and five-year survival rates in patients with non-small cell lung cancer (NSCLC). We evaluated PAK1 mRNA and protein expression in NSCLC cells and resected tumor specimens, as well...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33261184
DOI: 10.3390/molecules25235588
PMCID: PMC7729550

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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