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Article

Changes in frequency of IDDM-associated HLA DQB, CTLA4 and INS alleles.

International journal of immunogenetics - 1 Jun 2010

Witas H W, Jedrychowska-Dańska K, Zawicki P

Abstract excerpt

The incidence of type 1 diabetes is increasing worldwide. In Poland, the number of cases tripled during the last two decades. The aim of this study was to test the hypothesis that the increase may be at least partly explained by a shift in predisposing alleles' frequencies - resulting from treating the otherwise lethal disease, generally better health care as well as selective pressure imposed by pathogens...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20345871
DOI: 10.1111/j.1744-313X.2010.00896.x

Genes

CTLA4
INS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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