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Article

CTLA4+49G allele associates with early onset of type 1 diabetes in North Indians.

International journal of immunogenetics - 1 Dec 2015

Kumar N, Kaur G, Kanga U, Mehra N K, Neolia S C, Tandon N, Zucman S C

Abstract excerpt

Type 1 diabetes (T1D) is a complex autoimmune disease with strong genetic influence. In this study, we investigated +49A/G SNP (rs 231775) in exon 1 of cytotoxic T-lymphocyte-associated antigen 4 (CTLA4) by PCR-RFLP and its influence as a risk factor for the disease in the North Indian population. This polymorphism at codon 17 results in an amino acid substitution (Thr/Ala) in the leader peptide of the molecule....

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Source

Identifiers

PMID: 26385826
DOI: 10.1111/iji.12233

Genes

CTLA4

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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CTLA4+49G allele associates with early onset of type 1 diabetes in North Indians.PMID 26385826Read ↗

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