Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The SOD1 transgene expressed in erythroid cells alleviates fatal phenotype in congenic NZB/NZW-F1 mice.

Free radical research - 1 Jul 2016

Otsuki Noriyuki, Konno Tasuku, Kurahashi Toshihiro, Suzuki Saori, Lee Jaeyong, Okada Futoshi, Iuchi Yoshihito, Homma Takujiro, Fujii Junichi

Abstract excerpt

Oxidative stress due to a superoxide dismutase 1 (SOD1) deficiency causes anemia and autoimmune responses, which are phenotypically similar to autoimmune hemolytic anemia (AIHA) and systemic lupus erythematosus (SLE) in C57BL/6 mice and aggravates AIHA pathogenesis in New Zealand black (NZB) mice. We report herein on an evaluation of the role of reactive oxygen species (ROS) in a model mouse with inherited SLE,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease Models, Animal
Share to Erythroid Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lupus Erythematosus, Systemic

Share to Mice, Inbred NZB

Share to Superoxide Dismutase-1

Share to Survival Rate

Share to Transgenes

Source

Identifiers

PMID: 27080108
DOI: 10.1080/10715762.2016.1178388

Genes

SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The SOD1 transgene expressed in erythroid cells alleviates fatal phenotype in congenic NZB/NZW-F1 mice.PMID 27080108Read ↗

Elevated oxidative stress in erythrocytes due to a SOD1 deficiency causes anaemia and triggers autoantibody production.Semantic proximity Read ↗

A novel susceptibility locus on chromosome 2 in the (New Zealand Black x New Zealand White)F1 hybrid mouse model of systemic lupus erythematosus.Semantic proximity Read ↗

Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression.Semantic proximity Read ↗

The lupus phenotype in B6.NZBc1 congenic mice reflects interactions between multiple susceptibility loci and a suppressor locus.Semantic proximity Read ↗

New Zealand mixed mice: a genetic systemic lupus erythematosus model for assessing environmental effects.Semantic proximity Read ↗

Systemic lupus erythematosus--recent clues from congenic strains.Semantic proximity Read ↗

Development of ALS-like disease in SOD-1 mice deficient of B lymphocytesSemantic proximity Read ↗

The Lbw2 locus promotes autoimmune hemolytic anemia.Semantic proximity Read ↗

Inflammatory and oxidative stress phenotypes in transgenic sickle cell mice.Semantic proximity Read ↗

Mechanisms of peritoneal B-1a cells accumulation induced by murine lupus susceptibility locus Sle2.Semantic proximity Read ↗

Cutting Edge: A Role for CD1 in the Pathogenesis of Lupus in NZB/NZW MiceSemantic proximity Read ↗

A transgenic model of autoimmune hemolytic anemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.