Article
Elevated oxidative stress in erythrocytes due to a SOD1 deficiency causes anaemia and triggers autoantibody production.
The Biochemical journal - 1 Mar 2007
Iuchi Yoshihito, Okada Futoshi, Onuma Kunishige, Onoda Tadashi, Asao Hironobu, Kobayashi Masanobu, Fujii Junichi
Abstract excerpt
Reactive oxygen species are involved in the aging process and diseases. Despite the important role of Cu/Zn SOD (superoxide dismutase) encoded by SOD1, SOD1-/- mice appear to grow normally under conventional breeding conditions. In the present paper we report on a novel finding showing a distinct...
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