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Article

A telescope GWAS analysis strategy, based on SNPs-genes-pathways ensamble and on multivariate algorithms, to characterize late onset Alzheimer's disease.

Scientific reports - 21 Jul 2020

Squillario Margherita, Abate Giulia, Tomasi Federico, Tozzo Veronica, Barla Annalisa, Uberti Daniela

Abstract excerpt

Genome-wide association studies (GWAS) have revealed a plethora of putative susceptibility genes for Alzheimer's disease (AD), with the sole exception of APOE gene unequivocally validated in independent study. Considering that the etiology of complex diseases like AD could depend on functional multiple genes interaction network, here we proposed an alternative GWAS analysis strategy based on (i) multivariate...

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PMID: 32694537
DOI: 10.1038/s41598-020-67699-8
PMCID: PMC7374579

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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