Article
Testing for association with multiple traits in generalized estimation equations, with application to neuroimaging data.
NeuroImage - 1 Aug 2014
Zhang Yiwei, Xu Zhiyuan, Shen Xiaotong, Pan Wei
Abstract excerpt
There is an increasing need to develop and apply powerful statistical tests to detect multiple traits-single locus associations, as arising from neuroimaging genetics and other studies. For example, in the Alzheimer's Disease Neuroimaging Initiative (ADNI), in addition to genome-wide single nucleotide polymorphisms (SNPs), thousands of neuroimaging and neuropsychological phenotypes as intermediate phenotypes for...
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