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Article

Endothelial nitric oxide synthase tagSNPs influence the effects of enalapril in essential hypertension.

Nitric oxide : biology and chemistry - 1 May 2016

Oliveira-Paula Gustavo H, Lacchini Riccardo, Luizon Marcelo R, Fontana Vanessa, Silva Pamela S, Biagi Celso, Tanus-Santos Jose E

Abstract excerpt

The antihypertensive effects of angiotensin-converting enzyme inhibitors (ACEi) are associated with up-regulation of endothelial nitric oxide synthase (NOS3) activity. This mechanism may explain how polymorphisms in NOS3 gene affect the antihypertensive responses to ACEi. While clinically relevant NOS3 polymorphisms were previously shown to affect the antihypertensive responses to enalapril, no study has tested...

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Share to Angiotensin-Converting Enzyme Inhibitors
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27060232
DOI: 10.1016/j.niox.2016.03.006

Genes

NOS3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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