Article
Matrix metalloproteinase 9 -1562C/T polymorphism increased protein levels in patients with colorectal cancer in a sample from southeastern Brazil.
Genetics and molecular research : GMR - 31 Mar 2016
Hoelzle C R, Magalhães K C S F, Carvalho S S, Santos G A, Maia I M, Sousa M C P S, Andrade-Filho J S, Cruz G M G, Simões R T
Abstract excerpt
We examined whether the allelic and/or genotypic profile of locus -1562C/T of the matrix metalloproteinase (MMP-9) gene influences the protein expression levels of MMP-9 in patients with colorectal cancer (CRC) compared with controls. A total of 104 patients with CRC and 84 controls were evaluated. Peripheral blood was collected from both groups and DNA extraction was performed for -1562C/T genotyping; the plasma...
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