Association between MMP-9 -1562 C/T polymorphism and susceptibility to digestive cancers: A meta-analysis.

doi:10.1016/j.gene.2018.06.025

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Article

Association between MMP-9 -1562 C/T polymorphism and susceptibility to digestive cancers: A meta-analysis.

Gene - 5 Oct 2018

Hu Chaoliang, Weng Fangzhong, Li Lin, Dai Wei, Yan Jun, Peng Liqing, Zhou Ruixiang

Abstract excerpt

PURPOSE: Matrix metalloproteinases (MMPs) play important roles in tumorigenesis. The variant in MMP-9 -1562 C/T (single nucleotide polymorphisms labeled rs3918242) has been extensively evaluated as predisposing factors to digestive cancers susceptibility. However, most of these studies only contained a small number of subjects and they showed conflicting results. Therefore, to elucidate these associations, we...

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PMID: 29890308
DOI: 10.1016/j.gene.2018.06.025

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