Article
Association and Prognostic Significance of the Functional -1562C/T Polymorphism in the Promoter Region of MMP-9 in Turkish Patients with Gastric Cancer.
Pathology oncology research : POR - 1 Sept 2015
Avcı Nilufer, Ture Mehmet, Deligonul Adem, Cubukcu Erdem, Olmez Omer Fatih, Sahinturk Serdar, Topak Ali, Kurt Ender, Evrensel Turkkan, Şahin Ahmet Bilgehan, Yakut Tahsin
Abstract excerpt
Matrix metalloproteinases (MMPs) are a group of zinc-dependent peptidases that participate in matrix turnover in solid malignancies. The aim of this study was twofold. First, we sought to investigate under a case-control design the association between the functional -1562C/T polymorphism in the promoter region of MMP-9 and gastric cancer (GC) in a Turkish sample. Second, we examined its prognostic significance in...
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