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Article

Association of matrix metalloproteinase-2 and -9 promoter polymorphisms with colorectal cancer in Chinese.

Molecular carcinogenesis - 1 Nov 2007

Xu Enping, Xia Xiaoping, Lü Bingjian, Xing Xiaoming, Huang Qiong, Ma Yu, Wang Wei, Lai Maode

Abstract excerpt

Matrix metalloproteinase-2 (MMP-2) and -9 (MMP-9) play an important role in cancer initiation, invasion, and metastasis. The aim of this study was to investigate whether common genetic variants in these two key MMPs are associated with the development and progression of colorectal cancer in a Chinese population. We detected the MMP-2-790T/G, -955A/C, -1575G/A, and MMP-9-1562 C/T polymorphisms in 126 colorectal...

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PMID: 17546628
DOI: 10.1002/mc.20323

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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