Article
An Overview of Matrix Metalloproteinase 9 Polymorphism and Gastric Cancer Risk.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015
Verma Sugreev, Kesh Kousik, Gupta Arnab, Swarnakar Snehasikta
Abstract excerpt
Matrix metalloproteinase (MMP) 9, a key member of multifunctional family of zinc dependent endopeptidases has been found to be upregulated during inflammation and in some cancers. MMPs cleave extracellular matrix (ECM) proteins and play critical roles in cellular apoptosis, angiogenesis, tumor growth and metastasis. Several genetic polymorphisms have been identified that show allele specific effects on MMP9...
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