Article
Clinical characteristics of TIMP2, MMP2, and MMP9 gene polymorphisms in colorectal cancer.
Journal of gastroenterology and hepatology - 1 Feb 2011
Park Kyung Sook, Kim Seon Jeong, Kim Kyung Ho, Kim Jin Cheon
Abstract excerpt
BACKGROUND AND AIM: Genetic variations and the expression profile of matrix metalloproteinases (MMP) and tissue inhibitors of metalloproteinases (TIMP) are involved in the invasion and metastasis of colorectal cancer. METHODS: The gene profiles of TIMP2 and MMP were assayed from 333 colorectal cancer using polymerase chain reaction-restriction fragment length polymorphism. RESULTS: TIMP2-418*G/*G, TIMP2 303*G/*G...
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