Article
Matrix metalloproteinase-9-1562C>T polymorphism may increase the risk of lymphatic metastasis of colorectal cancer.
World journal of gastroenterology - 14 Sept 2007
Xing Li-Li, Wang Zhen-Ning, Jiang Li, Zhang Yong, Xu Ying-Ying, Li Juan, Luo Yang, Zhang Xue
Abstract excerpt
AIM: To explore the role of the matrix metalloproteinase-9 (MMP-9) polymorphism in colorectal cancer (CRC) in a northeast Chinese population. METHODS: Genotyping of MMP-9-1562C>T and 279R>Q polymorphisms was carried out on blood samples from 137 colorectal cancer patients and 199 controls using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Multivariate logistic regression models...
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