Article
Investigating the Frequency of the ERCC1 Gene C8092A Polymorphism in Iranian Patients with Advanced Gastric Cancer Receiving Platinum-based Chemotherapy.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2016
Mokmeli Sharareh, Tehrani Golnaz Asaadi, Zamiri Reza Eghdam, Bahrami Tayyeb
Abstract excerpt
BACKGROUND: Platinum compounds are the main drugs for treatment of advanced gastric cancer. Previous studies have shown that clinical outcome with platinum-based compounds depends on ERCC1 polymorphisms. The aim of this study was to investigate the frequency of a common polymorphism of ERCC1 gene (C8092A) in Iranian patients with advanced gastric cancer receiving platinum chemotherapy. MATERIALS AND METHODS:...
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