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Article

Predicting the outcome of platinum-based chemotherapies in epithelial ovarian cancer using the 8092C/A polymorphism of ERCC1: a meta-analysis.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Mar 2014

Li Yan, Hu Pei, Cao Yu, Wang Gui-ying, Wang Na, Zhou Rong-miao

Abstract excerpt

BACKGROUND: In the present study, we performed this meta-analysis to estimate the association between excision repair cross-complementation group 1 (ERCC1) gene polymorphism and clinical resistance to platinum-based chemotherapy in the patients with epithelial ovarian cancer (EOC). METHODS: A total of 10 studies consist of 1479 EOC patients relating ERCC1 rs11615C/T and rs3212986C/A polymorphisms to the response...

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Antineoplastic Agents
Carcinoma, Ovarian Epithelial
Disease-Free Survival
Drug Resistance, Neoplasm
Endonucleases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasms, Glandular and Epithelial

Ovarian Neoplasms

Platinum Compounds

Source

Identifiers

PMID: 24499239
DOI: 10.3109/1354750X.2014.882414

Genes

ERCC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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