Article
Association between polymorphisms of ERCC1 and survival in epithelial ovarian cancer patients with chemotherapy.
Pharmacogenomics - 1 Mar 2012
Yan Li, Shu-Ying Yang, Shan Kang, Yip Benjamin H K, Rong-Miao Zhou, Na Wang, Hai-Yan Sun
Abstract excerpt
AIM: We evaluated whether the ERCC1 polymorphisms had an effect on survival in epithelial ovarian cancer (EOC) patients with platinum-based chemotherapy. MATERIALS & METHODS: Clinical data of 209 EOC patients between 2002 and 2008 were reviewed. The genotypes of 19007T/C and 8092C/A polymorphisms were assessed in all patients using PCR-RFLP. RESULTS: The 19007T/C polymorphism was significantly associated with...
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