Genetic variability of DNA repair mechanisms influences chemotherapy outcome of gastric cancer.

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Article

Genetic variability of DNA repair mechanisms influences chemotherapy outcome of gastric cancer.

International journal of clinical and experimental pathology - 1 Jan 2015

Yu Hai, Wu Xinghua, Zhang Yonggang, Jin Zhihong, Li Guoxin, Zhao Haiping

Abstract excerpt

Genetic variability of DNA repair mechanisms influences chemotherapy treatment outcome of gastric cancer. We conducted a cohort study to investigate the role of ERCC1-ERCC2 gene polymorphisms in the chemotherapy response and clinic outcome of gastric cancer. Between March 2011 and March 2013, 228 gastric patients who were newly diagnosed with histopathology were enrolled in our study. Genotypes of ERCC1 rs11615,...

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Identifiers

PMID: 26097599
PMCID: PMC4466986

Genes

ERCC1
ERCC2

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Source receipt: pubmed, retrieved 7 Sept 2026.

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