Article
[Effect of polymorphisms of NF-κB and PXR on platinum-based chemotherapy for non-small cell lung cancer].
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences - 28 Mar 2016
Zhou Yaxing, Yang Pei, Liu Yingzhi, Wang Liansheng
Abstract excerpt
OBJECTIVE: To investigate the effect of polymorphisms of NF-κB rs230521, NF-κB rs4648068 and pregnane X receptor (PXR) rs3814058 on platinum-based chemotherapy for non-small cell lung cancer patients. METHODS: We collected 262 cases of non-small cell lung cancer patients, and then analyzed the genotypes of NF-κB and PXR by MassARRAY method. The impact of polymorphisms on efficacy, gastrointestinal toxicity and...
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