Article
The ATP7B genetic polymorphisms predict clinical outcome to platinum-based chemotherapy in lung cancer patients.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Aug 2014
Li Xiang-Ping, Yin Ji-Ye, Wang Ying, He Hui, Li Xi, Gong Wei-Jing, Chen Juan, Qian Chen-Yue, Zheng Yi, Li Fang, Yin Tao, Gong Zhi-Cheng, Zhou Bo-Ting, Zhang Yu, Xiao Ling, Zhou Hong-Hao, Liu Zhao-Qian
Abstract excerpt
This study aims to investigate the influence of ATP7B genetic polymorphism to platinum-based chemotherapy in Chinese Han lung cancer patients. A total of 338 Chinese Han lung cancer patients were enrolled in this study. All patients underwent at least two cycles of platinum-based chemotherapy. Four tag SNPs of ATP7B (rs1061472, rs9535826, rs7999812, and rs9535828) were selected to evaluate their impacts to...
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