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Article

Genome-wide Association Study on Platinum-induced Hepatotoxicity in Non-Small Cell Lung Cancer Patients.

Scientific reports - 23 Jun 2015

Cao Songyu, Wang Cheng, Ma Hongxia, Yin Rong, Zhu Meng, Shen Wei, Dai Juncheng, Shu Yongqian, Xu Lin, Hu Zhibin, Shen Hongbing

Abstract excerpt

Platinum-based chemotherapy has been shown to improve the survival of advanced non-small cell lung cancer (NSCLC) patients; the platinum-induced toxicity severely impedes the success of chemotherapy. Genetic variations, such as single nucleotide polymorphisms (SNPs), may contribute to patients' responses to the platinum-based chemotherapy. To identify SNPs that modify the risk of hepatotoxicity in NSCLC patients...

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Identifiers

PMID: 26100964
DOI: 10.1038/srep11556
PMCID: PMC4477405

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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