Article
Cortical Amyloid Burden Differences Across Empirically-Derived Mild Cognitive Impairment Subtypes and Interaction with APOE ɛ4 Genotype.
Journal of Alzheimer's disease : JAD - 29 Mar 2016
Bangen Katherine J, Clark Alexandra L, Werhane Madeline, Edmonds Emily C, Nation Daniel A, Evangelista Nicole, Libon David J, Bondi Mark W, Delano-Wood Lisa
Abstract excerpt
We examined cortical amyloid-β (Aβ) levels and interactions with apolipoprotein (APOE) ɛ4 genotype status across empirically-derived mild cognitive impairment (MCI) subgroups and cognitively normal older adults. Participants were 583 ADNI participants (444 MCI, 139 normal controls [NC]) with baseline florbetapir positron emission tomography (PET) amyloid imaging and neuropsychological testing. Of those with...
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