Article
Cognitive Heterogeneity and Risk of Progression in Data-Driven Subtle Cognitive Decline Phenotypes.
Journal of Alzheimer's disease : JAD - 1 Jan 2022
Thomas Kelsey R, Bangen Katherine J, Weigand Alexandra J, Ortiz Gema, Walker Kayla S, Salmon David P, Bondi Mark W, Edmonds Emily C
Abstract excerpt
BACKGROUND: There is increasing recognition of cognitive and pathological heterogeneity in early-stage Alzheimer's disease and other dementias. Data-driven approaches have demonstrated cognitive heterogeneity in those with mild cognitive impairment (MCI), but few studies have examined this heterogeneity and its association with progression to MCI/dementia in cognitively unimpaired (CU) older adults. OBJECTIVE: We...
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