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Article

Genome-wide significant results identified for plasma apolipoprotein H levels in middle-aged and older adults.

Scientific reports - 31 Mar 2016

Mather Karen A, Thalamuthu Anbupalam, Oldmeadow Christopher, Song Fei, Armstrong Nicola J, Poljak Anne, Holliday Elizabeth G, McEvoy Mark, Kwok John B, Assareh Amelia A, Reppermund Simone, Kochan Nicole A, Lee Teresa, Ames David, Wright Margaret J, Trollor Julian N, Schofield Peter W, Brodaty Henry, Scott Rodney J, Schofield Peter R, Attia John R, Sachdev Perminder S

Abstract excerpt

Apolipoprotein H (ApoH) is a multi-functional plasma glycoprotein that has been associated with negative health outcomes. ApoH levels have high heritability. We undertook a genome-wide association study of ApoH levels using the largest sample to date and replicated the results in an independent cohort (total N = 1,255). In the discovery phase, a meta-analysis of two cohorts, the Sydney Memory and Ageing Study...

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Identifiers

PMID: 27030319
DOI: 10.1038/srep23675
PMCID: PMC4814826

Genes

APOH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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