Article
The common insertional polymorphism in the APOC1 promoter is associated with serum apolipoprotein C-I levels in Hispanic children.
Atherosclerosis - 1 Apr 2005
Shachter Neil S, Rabinowitz Daniel, Stohl Sheldon, Conde-Knape Karin, Cohn Jeffrey S, Deckelbaum Richard J, Berglund Lars, Shea Steven
Abstract excerpt
We examined the effect of APOC1-317insCGTT allele status (HpaI RFLP, deletion [H1] and insertion [H2] alleles) on serum apolipoprotein (apo) C-I level in 362 Hispanic children in the Columbia University BioMarkers Study. The H2 allele was present in 147 subjects (40.6%). Serum apoC-I was 20% lower in the presence of the H2 allele in APOE epsilon3/epsilon3 homozygotes (P=0.003) but did not differ by H2 status in...
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