Article
Complete DNA sequence variation in the apolipoprotein H (beta-glycoprotein I) gene and identification of informative SNPs.
Annals of human genetics - 1 Jan 2006
Chen Qi, Kamboh M Ilyas
Abstract excerpt
Apolipoprotein H (APOH), also known as beta2-glycoprotein I, is a major antigen for the production of antiphospholipid antibodies in autoimmune diseases. Previously we have examined DNA variation in the coding region of the APOH gene and determined the molecular basis of the common protein polymorphism. Here we report the results of DNA sequence variation in the entire APOH gene encompassing a 20.3 kb region in...
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