Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-Wide Association Study Highlights APOH as a Novel Locus for Lipoprotein(a) Levels-Brief Report.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jan 2021

Hoekstra Mary, Chen Hao Yu, Rong Jian, Dufresne Line, Yao Jie, Guo Xiuqing, Tsai Michael Y, Tsimikas Sotirios, Post Wendy S, Vasan Ramachandran S, Rotter Jerome I, Larson Martin G, Thanassoulis George, Engert James C

Abstract excerpt

OBJECTIVE: Lp(a) (lipoprotein[a]) is an independent risk factor for cardiovascular diseases and plasma levels are primarily determined by variation at the LPA locus. We performed a genome-wide association study in the UK Biobank to determine whether additional loci influence Lp(a) levels. Approach and Results: We included 293 274 White British individuals in the discovery analysis. Approximately 93 095 623...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta 2-Glycoprotein I
Share to Biomarkers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cardiovascular Diseases

Share to Genetic Loci

Share to Genome-Wide Association Study

Share to Heart Disease Risk Factors

Share to Lipoprotein(a)

Share to Risk Assessment

Source

Open in PubMed Open full text

Identifiers

PMID: 33115273
DOI: 10.1161/ATVBAHA.120.314965
PMCID: PMC7769958

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-Wide Association Study Highlights APOH as a Novel Locus for Lipoprotein(a) Levels-Brief Report.PMID 33115273Read ↗

Genetics and Pathophysiological Mechanisms of Lipoprotein(a)-Associated Cardiovascular Risk.Semantic proximity Read ↗

Lipoprotein(a): new insights from modern genomicsSemantic proximity Read ↗

A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.Semantic proximity Read ↗

[Lipoprotein(a) - the hereditary risk factor for cardiovascular disease].Semantic proximity Read ↗

Evidence for several independent genetic variants affecting lipoprotein (a) cholesterol levels.Semantic proximity Read ↗

Ascertainment Bias in the Association Between Elevated Lipoprotein(a) and Familial Hypercholesterolemia.Semantic proximity Read ↗

Significance of lipoprotein(a) levels in familial hypercholesterolemia and coronary artery disease.Semantic proximity Read ↗

Variants in LPA are associated with familial hypercholesterolaemia: whole genome sequencing analysis in the 100 000 Genomes Project.Semantic proximity Read ↗

Cardiovascular Implications of Lipoprotein(a) and its Genetic VariantsSemantic proximity Read ↗

Evaluating genetically-predicted causal effects of lipoprotein(a) in human diseases: a phenome-wide Mendelian randomization studySemantic proximity Read ↗

Ancestry specific distribution of LPA Kringle IV-Type-2 genetic variants highlight associations to apo(a) copy number, glucose, and hypertensionSemantic proximity Read ↗

Proteomic analysis identifies lipoprotein(a)-associated proteins linked to incident atherosclerotic cardiovascular disease eventsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.