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Article

Analysis of CH25H in multiple sclerosis and neuromyelitis optica.

Journal of neuroimmunology - 15 Feb 2016

Forwell Amanda L, Bernales Cecily Q, Ross Jay P, Yee Irene M, Encarnacion Mary, Lee Joshua D, Sadovnick A Dessa, Traboulsee Anthony L, Vilariño-Güell Carles

Abstract excerpt

Oxysterols produced by CH25H during cholesterol metabolism have been shown to play an important role in the immune response. In this study we report the genetic characterization of CH25H in patients diagnosed with multiples sclerosis (MS) or neuromyelitis optica (NMO), for the identification of genetic variants affecting disease susceptibility and course. Exome analysis in 212 MS and 14 NMO patients identified a...

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Source

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Identifiers

PMID: 26857497
DOI: 10.1016/j.jneuroim.2015.12.014
PMCID: PMC5092160

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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