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[Tetracycline-inducible replications of wild-type and an adefovir-dipivoxil-resistant hepatitis B virus in human liver cells].

Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] - 1 Apr 2016

Wang J H, Wang X Y, Fei R, Zhang H Y, Wei L

Abstract excerpt

OBJECTIVE: To establish cell lines with inducible replications of wild-type or rtE218G, an adefovir-dipivoxil-resistant HBV mutant. METHODS: Tetracycline transactivator (tTA) was stably transfected into human liver cell line HepG2.1.2 folds of full-length of wild-type or rtE218G-mutated HBV genomes were cloned into the pTRE vector and cotransfected into the tTA-expressing cells with a linear selection marker for...

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Identifiers

PMID: 27029368
DOI: 10.3760/cma.j.issn.0253-9624.2016.04.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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