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Article

Productive HBV infection of well-differentiated, hNTCP-expressing human hepatoma-derived (Huh7) cells

29 Sept 2017

Abstract excerpt

Abstract Feasible and effective cell models for hepatitis B virus (HBV) infection are required for investigating the complete lifecycle of this virus, including the early steps of viral entry. Resistance to dimethyl sulfoxide/polyethylene glycol (DMSO/PEG), hNTCP expression, and a differentiated state are the limiting factors for successful HBV infection models. In the present study, we used a hepatoma cell line...

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PMID: 28971350
DOI: 10.1007/s12250-017-3983-x

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