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Article

A novel method for nucleos(t)ide analogues susceptibility assay of hepatitis B virus by viral polymerase transcomplementation.

Antiviral research - 1 Feb 2016

Luo Ying-ying, Tao Ying, Cai Xue-fei, Zhang Wen-lu, Long Quan-xin, Guo Haitao, Huang Ai-long, Hu Jie-li

Abstract excerpt

Nucleos(t)ide analogues (NUCs) susceptibility assay is important for the study of hepatitis B virus (HBV) drug resistance. The purpose of susceptibility assay is to test the sensitivity of a specific HBV variant to NUCs in vitro, by which assesses if and to what extent the mutant virus is resistant to a specific NUC. Among the existing susceptibility assay methods, stable cell line expressing the specific variant...

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PMID: 26738784
DOI: 10.1016/j.antiviral.2015.12.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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