Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Establishment of an inducible cell line for Hepatitis B virus genotype C2 and its pharmacological responses to interferons.

Pharmacological research - 1 Apr 2022

Jiang Shaodong, Wang Xin, Chen Kaili, Yang Pengyuan

Abstract excerpt

Hepatitis B virus (HBV) genotype C is closely associated with poor prognosis, contributing greatly to heavy chronic hepatitis B (CHB)-related liver disease burden in China and worldwide. However, the mechanistic studies on genotype C of HBV remain largely limited, partially because of a long-term lack of genotype C HBV-based stable cellular tools. According to a bioinformatics analysis on the sub-genotype C2 HBV...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line
Share to DNA, Viral
Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis B virus

Share to Interferons

Source

Identifiers

PMID: 35218895
DOI: 10.1016/j.phrs.2022.106142

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Establishment of an inducible cell line for Hepatitis B virus genotype C2 and its pharmacological responses to interferons.PMID 35218895Read ↗

Replication and Expression of the Consensus Genome of Hepatitis B Virus Genotype C from the Chinese Population.Semantic proximity Read ↗

In Vitro Systems for Studying Different Genotypes/Sub-Genotypes of Hepatitis B Virus: Strengths and Limitations.Semantic proximity Read ↗

HBV cccDNA─A Culprit and Stumbling Block for the Hepatitis B Virus Infection: Its Presence in Hepatocytes Perplexed the Possible Mission for a Functional CureSemantic proximity Read ↗

Chronic hepatitis B virus infection: epidemiology, prevention, and treatment in China.Semantic proximity Read ↗

Targeting the Achilles heel of the hepatitis B virus: a review of current treatments against covalently closed circular DNA.Semantic proximity Read ↗

Hepatitis B virus sensitivity to interferon-α in hepatocytes is more associated with cellular interferon response than with viral genotype.Semantic proximity Read ↗

On the history of hepatitis C virus cell culture systems.Semantic proximity Read ↗

The hepatitis C virus replicon system: from basic research to clinical application.Semantic proximity Read ↗

rt269I Type of Hepatitis B Virus (HBV) Leads to HBV e Antigen Negative Infections and Liver Disease Progression via Mitochondrial Stress Mediated Type I Interferon Production in Chronic Patients With Genotype C InfectionsSemantic proximity Read ↗

Classifying hepatitis B therapies with insights from covalently closed circular DNA dynamicsSemantic proximity Read ↗

Current status and future development of infectious cell-culture models for the major genotypes of hepatitis C virus: Essential tools in testing of antivirals and emerging vaccine strategies.Semantic proximity Read ↗

Intracellular interferon signalling pathways as potential regulators of covalently closed circular DNA in the treatment of chronic hepatitis BSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.