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Article

Development of a Functional Biomarker for Use in Cell-Based Therapy Studies in Seropositive Rheumatoid Arthritis.

Stem cells translational medicine - 1 May 2016

Shalev-Malul Gali, Soler David C, Ting Anthony E, Lehman Nicholas A, Barnboym Emma, McCormick Thomas S, Anthony Donald D, Lazarus Hillard M, Caplan Arnold I, Breitman Maya, Singer Nora G

Abstract excerpt

UNLABELLED: Cell-based therapy has potential therapeutic value in autoimmune diseases such as rheumatoid arthritis (RA). In RA, reduction of disease activity has been associated with improvement in the function of regulatory T cells (Treg) and attenuated responses of proinflammatory effector T cells (Teff). Mesenchymal stem cells (MSCs) and related multipotent adult progenitor cells (MAPC) have strong...

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Identifiers

PMID: 27025689
DOI: 10.5966/sctm.2015-0299
PMCID: PMC4835254

Genes

MSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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