Article
Enumeration and phenotypic characterization of synovial fluid multipotential mesenchymal progenitor cells in inflammatory and degenerative arthritis.
Arthritis and rheumatism - 1 Mar 2004
Jones Elena A, English Anne, Henshaw Karen, Kinsey Sally E, Markham Alex F, Emery Paul, McGonagle Dennis
Abstract excerpt
OBJECTIVE: To evaluate synovial fluid (SF) for the presence of mesenchymal progenitor cells (MPCs), to compare SF MPCs with bone marrow (BM) MPCs, and to enumerate these cells in both inflammatory arthritis and osteoarthritis (OA). METHODS: SF from 100 patients with arthritis (53 rheumatoid arthritis [RA], 20 OA, and 27 other arthropathies) was evaluated. To establish multipotentiality, polyclonal and single...
Topics
- Arthritis
- Arthritis, Rheumatoid
- Bone Marrow Cells
- Cell Count
- Cell Differentiation
- Cell Line
- Cells, Cultured
- Colony-Forming Units Assay
- Fibroblasts
- Humans
- Immunophenotyping
- Joint Diseases
- Mesenchymal Stem Cells