Article
Olfactory ecto-mesenchymal stem cells possess immunoregulatory function and suppress autoimmune arthritis.
Cellular & molecular immunology - 1 May 2016
Rui Ke, Zhang Zhijiang, Tian Jie, Lin Xiang, Wang Xiaohui, Ma Jie, Tang Xinyi, Xu Huaxi, Lu Liwei, Wang Shengjun
Abstract excerpt
Recent studies have identified olfactory ecto-mesenchymal stem cells (OE-MSCs) as a new type of resident stem cell in the olfactory lamina propria. However, it remains unclear whether OE-MSCs possess any immunoregulatory functions. In this study, we found that mouse OE-MSCs expressed higher transforming growth factor-beta and interleukin-10 levels than bone marrow-derived MSCs. In culture, OE-MSCs exerted their...
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